Subunit Rotavirus Vaccine Administered Parenterally to Rabbits Induces Active Protective Immunity
نویسندگان
چکیده
منابع مشابه
Subunit rotavirus vaccine administered parenterally to rabbits induces active protective immunity.
Virus-like particles (VLPs) are being evaluated as a candidate rotavirus vaccine. The immunogenicity and protective efficacy of different formulations of VLPs administered parenterally to rabbits were tested. Two doses of VLPs (2/6-, G3 2/6/7-, or P[2], G3 2/4/6/7-VLPs) or SA11 simian rotavirus in Freund's adjuvants, QS-21 (saponin adjuvant), or aluminum phosphate (AlP) were administered. Serol...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1998
ISSN: 1098-5514,0022-538X
DOI: 10.1128/jvi.72.11.9233-9246.1998